ODCs

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1 associated gene
No signs/symptoms info

PROTEIN INTERACTIONS: 1

1 OMIM reference -
2 associated genes
No signs/symptoms info

Severe early-onset obesity-insulin resistance syndrome due to SH2B1 deficiency

Familial medullary thyroid carcinoma

SH2B1	(UniProt - OMIM)		NTRK1	(UniProt - OMIM)
			RET	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	SH2B1	(0.86)	NTRK1

Citations in the biomedical literature:

Severe early-onset obesity-insulin resistance syndrome due to SH2B1 deficiency		Familial medullary thyroid carcinoma
	Synonym(s): (no synonyms)		Synonym(s): - Familial MTC

	Classification (Orphanet): - Rare endocrine disease - Rare genetic disease		Classification (Orphanet): - Rare endocrine disease - Rare gastroenterologic disease - Rare genetic disease - Rare oncologic disease

	Classification (ICD10): - Endocrine, nutritional and metabolic diseases -		Classification (ICD10): - Neoplasms -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: childhood Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: - Average age onset: - Average age of death: - Type of inheritance: autosomal dominant

	External references: No OMIM references No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: C536911

No signs/symptoms info available.